PRF Under Eye Filler: Procedure and Longevity of Results

Medically Reviewed
Medically Reviewed by Dr. Aurora Kalmanson on
Written by Fillers Editorial Team, plastic surgery specialists.

PRF (Platelet-Rich Fibrin) under eye filler is a cutting-edge aesthetic treatment that leverages your body’s natural healing components to rejuvenate the delicate under-eye area. Unlike traditional fillers, PRF utilizes a concentration of your own platelets, fibrin, and growth factors, derived from your blood, to stimulate collagen production and improve skin quality.

This innovative approach addresses concerns such as dark circles, puffiness, and the appearance of fine lines, offering a more natural and sustained solution to under-eye rejuvenation. With PRF, patients can achieve a refreshed look with minimal risk and downtime, making it an attractive option for those seeking a youthful and revitalized appearance.

Understanding PRF Under Eye Filler

PRF under eye filler represents a paradigm shift in aesthetic medicine, focusing on controling the body’s innate regenerative capabilities to address the common signs of aging around the eyes.

What is PRF and How is it Different from PRP?

Platelet-Rich Fibrin (PRF) is a second-generation platelet concentrate, widely considered an advancement over Platelet-Rich Plasma (PRP). While both PRF and PRP are derived from the patient’s own blood and contain growth factors that promote healing and rejuvenation, PRF is unique due to its slow and natural clotting process. This results in a fibrin matrix that releases growth factors over a longer period, offering enhanced and sustained benefits. PRF also contains a higher concentration of white blood cells and platelets, as well as a small number of stem cells, which further contribute to its regenerative properties. Unlike PRP, PRF does not require anticoagulants during processing, making it a purely natural filler option for under-eye treatment.

Benefits of PRF Over Traditional Fillers

Long-Term Benefits and Sustained Release: The longevity of PRF’s effects is a compelling advantage over conventional fillers. Traditional fillers offer immediate results, but their effects diminish over time, often requiring repeat sessions. In contrast, PRF promotes the body’s own regenerative mechanisms, leading to improvements that unfold gradually and last longer. The sustained release of growth factors from the fibrin matrix within PRF continues to stimulate tissue repair and collagen production over an extended period. This not only enhances the quality and durability of the aesthetic outcome but also means fewer treatments in the long run. Patients benefit from a more enduring rejuvenation, with results that integrate seamlessly with the natural aging process.

The PRF Under Eye Filler Procedure

The PRF under eye filler procedure is a multi-step process that begins with a thorough consultation and culminates in the strategic injection of PRF to rejuvenate the under-eye area.

Initial Consultation and Preparation

Blood Draw and Centrifugation: The first step in creating PRF under eye filler involves drawing a small amount of the patient’s blood, similar to a routine blood test. This blood is then processed using a centrifuge, a machine that spins the blood at a controlled speed to separate its components. The centrifugation is carefully calibrated to ensure that the platelets, fibrin, and white blood cells are concentrated while the red blood cells are removed. This process is crucial as it enriches the blood with the key elements needed for the regenerative treatment. The result is a potent mixture of growth factors and healing cells that form the basis of the PRF injectable.

Creating the PRF Injectable: Once the blood has been centrifuged, the upper layer containing the platelet-rich fibrin is carefully extracted. This golden-hued substance, often referred to as ‘liquid gold,’ is the PRF that will be used as the injectable filler. The PRF is rich in growth factors, stem cells, and healing proteins that are essential for tissue regeneration and repair. By harnessing these powerful components of the patient’s own blood, the PRF injectable is prepared to provide a natural and effective treatment for under-eye concerns. The preparation of PRF is a delicate process that requires precision and expertise to ensure the highest quality and efficacy of the injectable.

Injection Techniques for Under Eye Treatment

Cannula Technique for Minimizing Discomfort: The cannula technique is a modern approach to administering under eye fillers, including PRF, aimed at minimizing patient discomfort. Unlike traditional needles, a cannula is a thin, flexible tube with a blunt tip that is designed to navigate the delicate under-eye area with less trauma to the tissue. This method reduces the risk of bruising and swelling by allowing for fewer entry points and smoother product distribution. The use of a cannula also provides the injector with greater control and precision, ensuring a more comfortable experience for the patient. By minimizing discomfort and potential complications, the cannula technique enhances the overall patient experience during PRF under eye treatments.

Strategic Placement for Optimal Results: Strategic placement of PRF is crucial for achieving optimal results in under eye rejuvenation. Injectors must have a deep understanding of the anatomy and the unique contours of the under-eye area to ensure the PRF is administered effectively. The goal is to target areas where volume loss and skin laxity are most pronounced, providing a natural lift and reducing the appearance of dark circles. Precision in placement not only maximizes the aesthetic outcome but also ensures that the growth factors within PRF work efficiently to stimulate collagen production and tissue regeneration where it is needed most.

Post-Treatment Expectations and Recovery

Duration of the Appointment: The duration of a PRF under eye filler appointment is typically concise, often completed within an hour. This includes the time needed for the initial blood draw, centrifugation to create the PRF injectable, and the actual injection process. The efficiency of the procedure makes it a convenient option for patients with busy schedules. Despite the quick turnaround, the appointment is comprehensive, ensuring that each step is performed with care and precision to deliver the best possible results.

Immediate Aftercare: Following a PRF under eye treatment, immediate aftercare is relatively straightforward. Patients are advised to avoid touching or rubbing the treated area to prevent any potential displacement of the PRF. It is also recommended to stay upright for several hours post-treatment and to avoid strenuous activities for the rest of the day. This allows the PRF to settle properly and start the regeneration process. Keeping the area clean and following any personalized aftercare instructions provided by the practitioner will support a smooth recovery.

Frequently Asked Questions

How many PRF treatments are needed for optimal results?

Typically, 2 to 3 PRF treatments spaced 4 to 6 weeks apart are recommended for optimal results, with maintenance sessions as needed.

How long do the effects of PRF under eye filler last?

The effects of PRF under eye filler can last up to 18-24 months, with individual results varying based on lifestyle and skin condition.

Can PRF under eye treatment be combined with fillers?

Yes, PRF under eye treatment can be combined with fillers for enhanced volumizing and skin rejuvenation effects.

Is PRF treatment suitable for all skin types?

PRF treatment is generally suitable for all skin types, as it uses the patient's own biological material, minimizing the risk of adverse reactions.

What are the potential side effects of PRF under eye treatment?

Potential side effects may include mild swelling, bruising, and redness at the injection site, which typically resolve within a few days.

How long do PRF eye injections last?

PRF eye injections can provide improvements that last up to 18-24 months, with longevity influenced by individual factors and maintenance treatments.

What are the possible complications of PRF under-eye treatment?

Possible complications, though rare, can include infection, asymmetry, and prolonged swelling or bruising.

Who is an Ideal Candidate for PRF Under Eye Filler?

An ideal candidate is someone seeking a natural approach to under-eye rejuvenation, with realistic expectations and no contraindications to treatment.

Can PRF Under Eye Filler Address Dark Circles and Puffiness?

Yes, PRF under eye filler can help improve the appearance of dark circles and puffiness by stimulating collagen production and improving skin quality.

What Makes PRF a Preferred Choice for Under Eye Rejuvenation?

PRF is preferred for its natural, chemical-free approach and its ability to provide long-term benefits through sustained release of growth factors.

How Does PRF Compare to Surgical Options for Under Eye Concerns?

PRF offers a non-surgical, minimally invasive alternative to surgery, with less downtime and risk, while still effectively addressing under-eye concerns.

Are There Any Risks or Side Effects Associated with PRF Under Eye Filler?

Risks are minimal as PRF uses the patient's own blood, but side effects can include temporary swelling, bruising, and redness.


PRF under eye filler stands out as a natural, effective solution for under-eye rejuvenation. With the potential to address a range of concerns from dark circles to fine lines, PRF leverages the body's own healing mechanisms for long-lasting results. Ideal for those seeking alternatives to traditional fillers and surgical options, PRF treatments offer a promising avenue for achieving a refreshed, youthful appearance with minimal downtime and side effects.

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Mahmoodabadi, R. A., Golafshan, H. A., Pezeshkian, F., Shahriarirad, R., & Namazi, M. R. (2023). Evaluation of the Effect of Platelet-Rich Fibrin Matrix in the Correction of Periorbital Wrinkles: An Experimental Clinical Trial.

Hassan, H., Quinlan, D. J., & Ghanem, A. (2020). Injectable platelet-rich fibrin for facial rejuvenation: A prospective, single-center study.

Dr. Aurora Kalmanson

Always Consult a Medical Specialist

The information provided in this blog is for informational and educational purposes only and should not be interpreted as personalized medical advice. It's crucial to understand that while we are medical professionals, the insights and advice we provide are based on general research and studies. They are not tailored to individual health needs or conditions. Thus, it is essential to consult directly with a healthcare provider who can offer personalized medical advice relevant to your specific situation.