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Dissolving Under Eye Filler – Reversing Filler Effects Safely

Medically Reviewed
Medically Reviewed by Dr. Aurora Kalmanson on
Written by Fillers Editorial Team, plastic surgery specialists.

Dissolving under eye filler has become an increasingly common procedure as more individuals seek to correct or reverse the effects of dermal filler injections in this delicate area. The process involves using an enzyme called hyaluronidase to break down hyaluronic acid-based fillers, effectively “erasing” the treatment.

This option is particularly valuable for those experiencing complications, dissatisfaction with results, or a desire to return to their pre-filler appearance. The procedure is generally quick, with minimal discomfort, and can provide immediate visible changes. However, it’s crucial to understand that dissolving filler is a medical procedure that should only be performed by qualified professionals, as improper technique can lead to further complications. Patients considering this option should be aware of potential side effects, the possibility of multiple sessions being necessary, and the importance of allowing adequate time for healing before considering any new filler treatments.

The Dissolving Process

The process of dissolving under eye filler involves a series of carefully executed steps designed to safely and effectively break down hyaluronic acid-based fillers. This procedure requires expertise and precision to ensure optimal results while minimizing potential risks and complications.

Hyaluronidase Injections

What is Hyaluronidase?: Hyaluronidase is an enzyme that plays a crucial role in the process of dissolving dermal fillers. Naturally occurring in the human body, it breaks down hyaluronic acid, a key component of many soft tissue fillers. In medical aesthetics, synthetic versions of hyaluronidase are used as injectable solutions to reverse the effects of hyaluronic acid-based fillers. These formulations are specifically designed for cosmetic purposes and are available under brand names such as Hylenex and Vitrase. Hyaluronidase works by temporarily increasing tissue permeability, allowing for the rapid breakdown and absorption of hyaluronic acid. While primarily used for dissolving fillers, it also has applications in other medical fields, such as enhancing the spread of local anesthetics.

How it Works on Hyaluronic Acid Fillers: Hyaluronidase functions by targeting the chemical bonds that hold hyaluronic acid molecules together in dermal fillers. When injected into an area treated with hyaluronic acid filler, the enzyme rapidly begins to break down these bonds, effectively liquefying the gel-like filler material. This process allows the body to metabolize and absorb the dissolved filler more quickly than it would naturally. The speed and extent of filler dissolution depend on several factors, including the type and concentration of hyaluronic acid filler used, the amount of hyaluronidase injected, and the specific area being treated. In the delicate under eye region, the process is particularly effective due to the thin skin and the typically small amount of filler used. Results can often be seen within hours, with full effects visible within 24 to 48 hours after treatment.

Procedure Overview

Consultation and Assessment: The consultation and assessment phase is a critical first step in the process of dissolving under eye filler. During this initial meeting, a qualified practitioner thoroughly evaluates the patient’s concerns, medical history, and the current state of their under eye filler. This assessment includes a detailed examination of the treated area to determine the extent of filler present, its placement, and any complications that may have arisen. The practitioner will discuss the patient’s reasons for seeking dissolution, whether it’s due to dissatisfaction with results, complications, or a desire for a different aesthetic approach. It’s also an opportunity to set realistic expectations about the outcome of the dissolving process and to discuss potential risks and side effects. The practitioner may take photographs for documentation and comparison purposes. Based on this comprehensive evaluation, an adapted treatment plan is developed, including the amount of hyaluronidase needed and the optimal injection technique for the individual’s specific case.

Ultrasound Guidance for Precision: Ultrasound guidance has emerged as a valuable tool in the precise and safe dissolution of under eye fillers. This advanced technique allows practitioners to visualize the exact location and distribution of filler material beneath the skin, as well as important anatomical structures such as blood vessels. By using ultrasound, the injector can accurately target the filler, minimizing the risk of injecting hyaluronidase into unintended areas or affecting natural tissues. This level of precision is particularly crucial in the under eye area due to its delicate nature and complex anatomy. Ultrasound guidance also helps in determining the optimal amount of hyaluronidase needed, preventing over-dissolution which could lead to hollowness or contour irregularities. Additionally, it aids in identifying any filler migration or unexpected placement, ensuring a more comprehensive and effective dissolution process. This technology significantly enhances the safety profile of the procedure and can lead to more satisfactory outcomes for patients.

Injection Techniques and Massage: The injection technique for dissolving under eye filler requires a high level of skill and precision. Practitioners typically use very fine needles or cannulas to administer hyaluronidase into the areas where filler is present. The injection depth and angle are crucial factors, as the goal is to target the filler without affecting surrounding tissues. Multiple small injections are often performed across the treatment area to ensure even distribution of the enzyme. Immediately following the injections, a gentle massage is usually performed. This massage serves several purposes: it helps to distribute the hyaluronidase evenly throughout the treated area, ensures contact with all of the filler material, and can help to break up any lumps or irregularities. The massage also promotes the absorption of the dissolved filler by stimulating lymphatic drainage. Patients may be instructed to continue gentle massage at home to enhance the dissolution process.

Results and Timeline

Immediate Effects: The immediate effects of dissolving under eye filler with hyaluronidase can be quite dramatic. Within minutes of the injection, patients may notice a softening of the treated area as the enzyme begins to break down the hyaluronic acid filler. This initial change is often accompanied by a slight swelling or puffiness, which is a normal reaction to the injection process and the enzymatic activity. Some patients report a sensation of warmth or tingling in the treated area, which is typically short-lived. In cases where the filler was causing visible lumps or irregularities, these may begin to smooth out relatively quickly. However, it’s important to note that the full extent of the dissolution is not immediately apparent, as the process continues to work over the next several hours. Patients are usually advised to avoid touching or manipulating the area excessively during this initial period to allow the hyaluronidase to work effectively.

Final Results in 24-48 Hours: The full effects of hyaluronidase on under eye filler become most apparent within 24 to 48 hours after the treatment. During this time, the enzyme continues to break down the hyaluronic acid filler, and the body begins to metabolize and absorb the dissolved material. Patients typically notice a significant reduction in the volume of the previously filled area, with many reporting that their under eye region looks much closer to its pre-filler state. Any swelling from the injection process usually subsides within this timeframe, allowing for a clearer assessment of the results. The skin may appear smoother, and issues such as puffiness or an overfilled appearance should be markedly improved. It’s during this period that both the practitioner and the patient can best evaluate the outcome of the dissolving process and determine if the desired result has been achieved or if further treatment may be necessary.

Possible Need for Multiple Sessions: While many patients achieve their desired results with a single hyaluronidase treatment, some cases may require multiple sessions to fully dissolve under eye filler. This need for additional treatments can arise due to several factors. The type and amount of filler initially injected play a significant role; more cross-linked or higher-density fillers may be more resistant to dissolution. Additionally, if the filler has been in place for an extended period, it may have integrated with the surrounding tissues, making complete dissolution more challenging. In some instances, practitioners may intentionally use a conservative approach in the first session to avoid over-correction, requiring a follow-up treatment. Patients are typically asked to return for a review appointment about two weeks after the initial dissolution treatment. At this time, the practitioner can assess the results and determine if further hyaluronidase injections are needed to achieve the optimal outcome.

Risks and Side Effects of Dissolving Fillers

While dissolving under eye fillers is generally considered safe, it’s important to be aware of potential risks and side effects. These can range from common, mild reactions to rare but more serious complications. Understanding these risks helps patients make informed decisions and manage expectations.

Common Side Effects

Bruising and Swelling: Bruising and swelling are among the most common side effects experienced after dissolving under eye fillers. These reactions occur due to the injection process itself and the enzymatic action of hyaluronidase. Bruising results from minor damage to blood vessels during the injection, while swelling is a natural inflammatory response to the treatment. The delicate nature of the under eye area makes it particularly prone to these effects. Bruising typically appears as purple or bluish marks that may spread slightly before fading, usually resolving within 7-10 days. Swelling can cause temporary puffiness or a slightly ‘pillowy’ appearance around the eyes, which generally subsides within 24-72 hours. To minimize these effects, patients are often advised to apply cold compresses and avoid blood-thinning medications or supplements prior to treatment.

Tenderness and Redness: Tenderness and redness in the treated area are common and typically short-lived side effects of dissolving under eye fillers. The tenderness is often described as a mild soreness or sensitivity to touch, which can persist for a few days after the procedure. This discomfort is usually manageable without pain medication. Redness occurs due to the body’s inflammatory response to the injection and the action of hyaluronidase. It may appear as a general flush or as small, pinpoint marks at the injection sites. The redness usually fades within a few hours to a day, but in some cases, it may last up to 48 hours. These symptoms are generally considered a normal part of the healing process. Patients are often advised to avoid applying makeup or skincare products to the area for at least 24 hours to reduce the risk of irritation and allow the skin to recover naturally.

Rare Complications

Allergic Reactions: While rare, allergic reactions to hyaluronidase can occur and are a serious concern when dissolving under eye fillers. These reactions can range from mild to severe, with symptoms potentially including itching, rash, swelling beyond the injection site, difficulty breathing, or in extreme cases, anaphylaxis. The risk is higher in individuals with a history of allergies, particularly to bee or wasp stings, as hyaluronidase is also present in their venom. To mitigate this risk, many practitioners perform a small skin test before the full treatment. It’s crucial for patients to disclose any allergies or previous adverse reactions to injectable treatments. In the event of an allergic reaction, immediate medical attention is necessary. For this reason, dissolving treatments should only be performed in clinical settings equipped to handle such emergencies.

Skin Contour Irregularities: Skin contour irregularities are a potential complication that can occur after dissolving under eye fillers. This issue may arise if the hyaluronidase is not evenly distributed or if it affects the natural hyaluronic acid in the skin unevenly. Patients might notice small depressions, asymmetry, or an overall uneven texture in the treated area. In some cases, excessive dissolution can lead to a hollowed or sunken appearance, particularly if the original filler was compensating for volume loss. These irregularities are often temporary, resolving as the body naturally replenishes its hyaluronic acid stores. However, in some instances, they may persist and require further treatment. To minimize this risk, practitioners often use precise injection techniques and may opt for a staged approach, dissolving small amounts of filler over multiple sessions. Patients should be aware that achieving perfectly smooth contours may take time and possibly additional treatments.

Potential for Overcorrection

Hollowness or Depressions: Hollowness or depressions can occur as a result of overcorrection when dissolving under eye fillers. This happens when too much hyaluronidase is used or when it affects the body’s natural hyaluronic acid in addition to the filler. The under eye area, being naturally prone to volume loss, can appear sunken or hollow if all the filler is removed without considering the underlying anatomy. Patients may notice a more pronounced tear trough or increased shadowing, which can make them look tired or older. This effect can be particularly distressing if the original filler was placed to correct existing hollowness. In some cases, the skin may appear thin or crepey due to the sudden loss of volume support. While these effects are often temporary as the body replenishes its natural hyaluronic acid, they can persist for several weeks or even months in some individuals.

Need for Additional Treatments: The need for additional treatments following the dissolution of under eye fillers is a common consideration, especially in cases of overcorrection. If hollowness or depressions occur, patients may require further interventions to restore a balanced, rejuvenated appearance. These treatments might include the careful reapplication of dermal fillers, but only after sufficient time has passed to allow the effects of hyaluronidase to fully subside, typically at least two weeks. In some cases, practitioners may recommend alternative treatments such as platelet-rich plasma (PRP) injections or microneedling to stimulate collagen production and improve skin quality. For patients with significant volume loss, a combination approach might be necessary. It’s crucial for patients to understand that achieving optimal results may require a staged approach, with multiple sessions spaced over time to gradually and safely restore volume and contour to the under eye area.

Frequently Asked Questions

Can all under eye fillers be dissolved?

Most under eye fillers made of hyaluronic acid can be dissolved using hyaluronidase. However, fillers containing other materials, such as calcium hydroxylapatite or poly-L-lactic acid, cannot be dissolved with hyaluronidase and require different approaches for correction.

How long does it take for hyaluronidase to work?

Hyaluronidase starts to work almost immediately, with visible changes occurring within minutes. However, the full effects are typically seen within 24 to 48 hours, as the enzyme continues to break down the hyaluronic acid filler during this period.

Is dissolving under eye filler painful?

Dissolving under eye filler can cause some discomfort, such as a stinging or burning sensation during the injection. A topical numbing cream is often applied beforehand to minimize pain, and any discomfort usually subsides quickly.

How much does dissolving under eye filler cost?

The cost of dissolving under eye fillers can vary depending on the clinic and the extent of the treatment required. Generally, prices range from $300 to $600 per session. It is best to consult with your practitioner for an accurate estimate based on your specific needs.

Can I get new fillers immediately after dissolving old ones?

It is generally recommended to wait at least two weeks after dissolving old fillers before getting new ones. This waiting period allows any swelling to subside and ensures that the hyaluronidase has fully taken effect, providing a clear baseline for new filler application.

Are there any alternatives to dissolving under eye fillers?

If you are not a candidate for hyaluronidase or prefer not to dissolve your fillers, alternatives include waiting for the filler to naturally degrade over time or undergoing non-invasive treatments like radiofrequency or laser therapy to improve under eye appearance.

Conclusion

Dissolving under eye fillers can provide a solution for those experiencing complications or dissatisfaction with their results. Using hyaluronidase, practitioners can efficiently break down hyaluronic acid-based fillers, restoring a more natural appearance. While the procedure is generally safe, patients should be aware of potential risks and side effects, and consult with a qualified professional to ensure the best outcomes. Understanding the process, from initial consultation to final results, allows individuals to make informed decisions about their aesthetic treatments and achieve their desired look.

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References:

Wilde, C. L., Jiang, K., Lee, S., & Ezra, D. G. (2024). The Posthyaluronidase Syndrome: Dosing Strategies for Hyaluronidase in the Dissolving of Facial Filler and Independent Predictors of Poor Outcomes.

https://journals.lww.com/prsgo/fulltext/2024/04000/the_posthyaluronidase_syndrome__dosing_strategies.55.aspx

Kroumpouzos, G., & Treacy, P. (2024). Hyaluronidase for Dermal Filler Complications: Review of Applications and Dosage Recommendations.

https://derma.jmir.org/2024/1/e50403

Dr. Aurora Kalmanson

Always Consult a Medical Specialist

The information provided in this blog is for informational and educational purposes only and should not be interpreted as personalized medical advice. It's crucial to understand that while we are medical professionals, the insights and advice we provide are based on general research and studies. They are not tailored to individual health needs or conditions. Thus, it is essential to consult directly with a healthcare provider who can offer personalized medical advice relevant to your specific situation.