Best Filler for Hands: Solutions for Aging Signs

Medically Reviewed
Medically Reviewed by Dr. Aurora Kalmanson on
Written by Fillers Editorial Team, plastic surgery specialists.

The quest for youthful hands has led many to discover the transformative power of dermal fillers. As the hands age, they often betray our years with wrinkles, volume loss, and prominent veins.

The best fillers for hands, such as Radiesse and Restylane Lyft, are FDA-approved solutions that address these concerns by restoring volume and stimulating collagen production. These treatments offer a non-surgical route to smoother, plumper hands, with results that can last up to a year or more. Whether you’re looking to diminish signs of aging or simply rejuvenate the appearance of your hands, fillers provide a quick, effective, and long-lasting solution.

Types of Hand Fillers and Their Unique Advantages

Hand fillers come in various formulations, each with unique properties and advantages. Choosing the right type can enhance the appearance of the hands, addressing specific concerns such as volume loss and skin texture.

Hyaluronic Acid Fillers

Restylane Lyft: Restylane Lyft is a hyaluronic acid-based filler that is FDA-approved for hand rejuvenation. Its robust formulation is designed to correct volume loss and reduce the appearance of wrinkles on the back of the hands. Restylane Lyft provides immediate volume and a smoother surface, offering a quick and noticeable improvement in hand appearance. Its effects can last up to six months or more, and because it is a hyaluronic acid filler, it can be dissolved if necessary, providing an extra layer of safety for patients.

Juvederm: Juvederm is another hyaluronic acid filler that is widely used for hand treatments. Known for its smooth consistency, Juvederm integrates well with the skin’s natural tissue, providing a soft and natural feel. It is particularly effective at smoothing fine lines and providing a subtle lift to the skin, which can make the hands look more youthful and refreshed. The results from Juvederm can last up to a year, making it a durable option for hand rejuvenation.

Volite: Volite is an innovative hyaluronic acid filler designed to improve skin quality by enhancing hydration and elasticity. While it does provide some volume, its primary benefit is in boosting skin health, resulting in hands that not only look younger but also feel more supple and resilient. Volite treatments can improve skin texture and firmness, and the benefits can be seen for up to six months after a single treatment session.

Calcium Hydroxylapatite Fillers

Radiesse (Calcium Hydroxylapatite as a Bio-Stimulant): Radiesse is a unique hand filler made from calcium hydroxylapatite, a substance that not only provides immediate volume but also acts as a bio-stimulant to encourage natural collagen production. This dual-action filler offers both immediate and long-term benefits, as the gel provides volume while the calcium particles stimulate the body to produce new collagen. The result is hands that have improved volume and skin quality, with effects that can last up to 18 months, making Radiesse a long-lasting solution for hand rejuvenation.

Collagen Biostimulants

Ellanse: Ellanse acts as a collagen biostimulant and is known for its longer-lasting effects in hand rejuvenation. Unlike traditional fillers that primarily add volume, Ellanse works by stimulating the body’s own collagen production, leading to gradual and natural-looking results. The filler is composed of polycaprolactone microspheres, which are biodegradable and safely absorbed by the body over time. As the microspheres stimulate collagen, the skin’s structure is reinforced, and volume is restored in a way that can last up to four years. Ellanse is particularly suited for patients looking for durable results and those interested in improving the overall quality of their skin.

Skin Boosters

Profhilo: Profhilo is a skin booster that stands out due to its high concentration of hyaluronic acid, designed to hydrate the skin and stimulate collagen and elastin production. Unlike traditional fillers that primarily address volume loss, Profhilo improves skin texture, elasticity, and hydration. It is injected in a unique pattern to provide an overall rejuvenating effect. The treatment is ideal for individuals with crepey skin who wish to achieve a more youthful and radiant appearance. Profhilo’s benefits are typically observed after two treatment sessions, spaced four weeks apart, and can last up to six months.

Frequently Asked Questions

How long do hand fillers last?

The longevity of hand fillers varies by type; hyaluronic acid fillers can last up to 12 months, while others like Radiesse may last up to 18 months.

Are hand fillers safe?

Hand fillers are generally safe when administered by a qualified and experienced practitioner, with most side effects being temporary and mild.

Can hand fillers be reversed?

Yes, hyaluronic acid-based fillers can be reversed with an enzyme called hyaluronidase if the results are unsatisfactory.

How do I choose the best filler for my hands?

The best filler for your hands should be determined by a qualified practitioner based on your aesthetic goals, hand anatomy, and medical history.

Are hand fillers painful?

Hand fillers may cause some discomfort, but pain can be minimized with topical numbing agents or local anesthesia.

How much downtime is needed after hand filler treatment?

Typically, no downtime is required, but it's advised to avoid strenuous activities for the first 24 hours after treatment.

Can hand fillers be reversed if I'm not satisfied with the results?

Yes, hyaluronic acid fillers can be dissolved, making them a reversible option if you're not satisfied with the results.

How do I know if I'm a good candidate for hand fillers?

Good candidates for hand fillers are those looking to address volume loss, wrinkles, and other signs of aging on their hands.


Hand fillers are a versatile and effective solution for combating the signs of aging hands, offering both aesthetic and functional benefits. With a variety of fillers available, adapted treatments can address individual concerns, from volume loss to skin texture improvements. While generally safe, it's crucial to choose an experienced and qualified practitioner to minimize risks and ensure optimal results. Maintenance treatments can prolong the effects, and with the possibility of reversal for certain fillers, patients can approach hand rejuvenation with confidence.

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Har-Shai, L., Ofek, S. E., Lagziel, T., Pikkel, Y. Y., Duek, O. S., Ad-El, D. D., & Shay, T. (2023). Revitalizing Hands: A Comprehensive Review of Anatomy and Treatment Options for Hand Rejuvenation.!/

Dr. Aurora Kalmanson

Always Consult a Medical Specialist

The information provided in this blog is for informational and educational purposes only and should not be interpreted as personalized medical advice. It's crucial to understand that while we are medical professionals, the insights and advice we provide are based on general research and studies. They are not tailored to individual health needs or conditions. Thus, it is essential to consult directly with a healthcare provider who can offer personalized medical advice relevant to your specific situation.