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Masseter Bulging After Botox – Managing and Correcting PMB

Medically Reviewed
Medically Reviewed by Dr. Aurora Kalmanson on
Written by Fillers Editorial Team, plastic surgery specialists.

Masseter bulging after botox injections is a rare but potential side effect of treatments aimed at reducing jaw muscle size or treating bruxism. This paradoxical effect, known as Paradoxical Masseteric Bulging (PMB), occurs in 5% to 18.8% of cases.

It manifests as an enlargement or protrusion of the masseter muscle when biting down or clenching, often appearing as a round, ball-like shape. While initially concerning, PMB is generally manageable and treatable with proper understanding and intervention.

Paradoxical Masseteric Bulging (PMB)

Paradoxical Masseteric Bulging is an uncommon complication that can occur following botox injections into the masseter muscle. Understanding its underlying mechanisms is crucial for both prevention and treatment.

Definition and Incidence Rate

Paradoxical Masseteric Bulging refers to the unexpected enlargement or protrusion of the masseter muscle following botox injections intended to reduce its size or activity. This condition manifests as a visible bulging of the muscle, particularly when the patient bites down or clenches their jaw. The incidence rate of PMB varies significantly, ranging from 0.5% to 18.8% of cases, as reported in recent literature. This wide range suggests that the occurrence of PMB may depend on various factors, including injection technique, individual anatomy, and the specific formulation of botox used.

Causes of PMB

Uneven Distribution of Botox Due to DIT: The primary cause of PMB is often related to the presence of a deep inferior tendon (DIT) within the masseter muscle. This broad tendon structure, located in the superficial layer of the muscle, can act as a barrier, preventing the even distribution of botox throughout the muscle fibers. When botox is injected beneath the DIT, it may be blocked from reaching the more superficial muscle fibers, creating a discrepancy in contractile ability between the deep and superficial layers of the muscle.

Overcompensation of Superficial Muscle Fibers: In cases where botox is primarily concentrated in the deeper layers of the masseter, the superficial muscle fibers may remain unaffected. As a result, these untreated fibers can overcompensate for the paralyzed deeper fibers, leading to visible bulging when the muscle is contracted. This overcompensation is the body’s natural response to maintain jaw function, but it results in the paradoxical appearance of muscle enlargement rather than the intended reduction.

Variability in Individual Anatomy: The anatomy of the masseter muscle can vary significantly among individuals, contributing to the unpredictable occurrence of PMB. Factors such as the thickness of the muscle, the specific orientation of muscle fibers, and the overall volume of the masseter can influence how botox affects muscle relaxation. Additionally, the division pattern of the DIT within the muscle can differ from person to person, further complicating the predictability of botox distribution and its effects on muscle contraction patterns.

Injection Technique and Placement: The proper technique and placement of botox injections are crucial in preventing paradoxical masseteric bulging. Practitioners should aim for a layer-by-layer approach, ensuring even distribution of the toxin throughout the masseter muscle. This involves identifying the full extent of the muscle and its anatomical landmarks through visualization and palpation while the patient is clenching their jaw. Injections should be carefully administered into both the superficial and deep bellies of the masseter, taking into account the potential presence of the deep inferior tendon. Multiple injection points, typically 3 to 5, are recommended to achieve uniform distribution. The dosage should be adapted to the individual patient’s needs, usually ranging from 20 to 50 units per side. Proper technique also involves using the correct needle length to reach the intended muscle depth while avoiding surrounding structures.

Symptoms and Appearance of PMB

Bulging or Protrusion of Masseter Muscle: The primary and most noticeable symptom of paradoxical masseteric bulging is the visible enlargement or protrusion of the masseter muscle. This bulging becomes particularly apparent when the patient bites down or clenches their jaw. Instead of the expected slimming effect from botox treatment, affected individuals may notice a rounded, ball-like shape in the lower part of their cheek. This protrusion can be unilateral or bilateral, depending on the injection sites and the individual’s muscle anatomy. The bulging may feel firm to the touch and can be more pronounced when viewed from certain angles, especially in profile. It’s important to note that this bulging is not due to muscle growth but rather an uneven contraction of muscle fibers, with some areas remaining active while others are paralyzed by the botox.

Asymmetry in Facial Contour: Paradoxical masseteric bulging can lead to noticeable asymmetry in facial contour, particularly affecting the lower third of the face. This asymmetry may manifest as an uneven jawline or differences in cheek fullness between the two sides of the face. In some cases, one side may appear slimmer (the intended effect of the botox treatment), while the other side shows unexpected bulging. This discrepancy can be subtle or quite pronounced, depending on the severity of the paradoxical reaction. The asymmetry is often more noticeable when the patient smiles or clenches their teeth, as these actions engage the masseter muscle. This unexpected outcome can be distressing for patients who sought treatment to achieve a more balanced and harmonious facial appearance.

Timing of Symptom Onset: The onset of symptoms related to paradoxical masseteric bulging typically occurs within the first two weeks following botox injection. However, the exact timing can vary among individuals. Some patients may notice changes as early as a few days after treatment, while others might not observe any bulging until the full effects of botox have set in, which is usually around 14 days post-injection. It’s important to note that the appearance of bulging may not be immediate, as it takes time for the botox to fully affect the muscle fibers. Additionally, the timing of symptom onset can be influenced by factors such as the patient’s muscle anatomy, the dosage of botox used, and the specific injection technique employed. Patients should be advised to monitor their facial appearance closely during this initial two-week period and report any unexpected changes to their healthcare provider promptly.

Correction of Paradoxical Masseteric Bulging

When paradoxical masseteric bulging occurs, prompt and accurate correction is essential to restore facial aesthetics and patient satisfaction. The following approaches focus on addressing the underlying causes of bulging through targeted interventions.

Additional Botox Injections

Targeting Paradoxically Contracted Muscle Fibers: When correcting paradoxical masseteric bulging, the focus is on precisely targeting the muscle fibers that are causing the unwanted protrusion. These fibers are typically located in areas where the initial botox treatment did not effectively reach or paralyze the muscle. The practitioner must carefully identify the specific regions of the masseter that are still actively contracting and causing the bulging appearance. This often involves a combination of visual assessment and palpation while the patient clenches their jaw. The goal is to administer additional botox injections directly into these hyperactive areas, ensuring that the toxin reaches the problematic muscle fibers. By selectively weakening these overactive portions of the muscle, the overall contour of the masseter can be smoothed out, reducing the appearance of bulging and restoring a more balanced facial appearance.

Dosage and Placement Considerations: When administering additional botox injections to correct paradoxical masseteric bulging, careful consideration of dosage and placement is crucial. The dosage for corrective treatment is typically lower than the initial treatment, often ranging from 10 to 20 units per side, depending on the severity of bulging and individual patient factors. It’s important to start with a conservative amount and reassess after two weeks, as over-correction can lead to excessive weakening of the muscle. Placement of these corrective injections should be highly targeted, focusing specifically on the areas of visible bulging. Multiple small injections are often preferred over a single large dose to ensure even distribution. The depth of injection may vary depending on whether the bulging is more superficial or deep within the muscle. Practitioners should also consider the patient’s overall facial balance and aesthetic goals when determining the exact placement of corrective injections to achieve a harmonious result.

Timeline for Improvement and Complete Correction

Initial Results Within 1 Week: After administering corrective botox injections for paradoxical masseteric bulging, patients can typically expect to see initial improvements within the first week. This rapid response is due to the localized and targeted nature of the additional injections. During this period, patients may notice a gradual softening of the bulging area and a subtle reduction in the prominence of the affected masseter muscle. The speed and extent of these initial improvements can vary depending on factors such as the individual’s muscle anatomy, the severity of the bulging, and the precise dosage and placement of the corrective injections. It’s important for practitioners to inform patients that while some changes may be noticeable within this timeframe, the full effects of the treatment are still developing. Patients should be encouraged to observe and document any changes they notice during this first week to facilitate accurate assessment at follow-up appointments.

Full Correction Within 2 Weeks: The complete correction of paradoxical masseteric bulging typically manifests within two weeks following the corrective botox injections. This timeframe allows for the full onset of botox’s effects on the targeted muscle fibers. By the end of the second week, patients should observe a significant reduction in the bulging appearance, with the masseter muscle taking on a more balanced and symmetrical contour. The facial profile often appears more refined and in line with the initial aesthetic goals of the treatment. It’s crucial for practitioners to schedule a follow-up appointment around this two-week mark to assess the results completely. During this evaluation, any remaining asymmetries or areas of concern can be addressed. In some cases, minor adjustments or touch-ups might be necessary to achieve optimal results. Patients should be advised that while the full correction is generally achieved within this timeframe, the effects may continue to refine slightly over the subsequent weeks.

Frequently Asked Questions

How common is paradoxical masseteric bulging after masseter botox injections?

Paradoxical masseteric bulging is relatively uncommon, with an incidence rate ranging from 0.5% to 18.8%. This variability depends on factors such as injection technique, individual anatomy, and practitioner expertise.

Can PMB be prevented with proper injection techniques?

Yes, PMB can often be prevented with proper injection techniques. Ensuring even distribution of Botox through layer-by-layer injections and adapting the treatment to the individual's anatomy are crucial steps in minimizing the risk of PMB.

How long does it take for PMB to go away after corrective injections?

After corrective botox injections, initial improvements in PMB can be observed within one week, with full correction typically achieved within two weeks.

Is PMB a permanent side effect of masseter Botox injections?

No, PMB is not a permanent side effect. It can usually be corrected with additional targeted botox injections, and the condition often resolves fully within two weeks.

Can PMB occur even with experienced injectors?

Yes, although the experience and skill of the injector significantly reduce the risk of PMB, it can still occur due to individual anatomical variations and other factors beyond the injector's control.

Are there any long-term consequences of experiencing PMB?

There are generally no long-term consequences of experiencing PMB, as it is typically corrected with additional botox injections. However, it is important to address it promptly to avoid prolonged discomfort or aesthetic concerns.

Conclusion

Paradoxical masseteric bulging is a manageable side effect of masseter botox injections. By employing proper techniques, such as even toxin distribution and adapted treatments, practitioners can effectively minimize the risk. Prompt recognition and corrective measures, like additional targeted injections, typically resolve PMB within two weeks. With the expertise of skilled injectors and a personalized approach, patients can achieve their desired aesthetic outcomes while mitigating potential complications. Always consult with a qualified professional for the best results and guidance throughout your treatment.

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References:

Sandhu, S., & Shaefer, J. (2024). Paradoxical masseteric bulging after botulinum neurotoxin type A injection.

https://casereports.bmj.com/content/17/5/e258568

Rice, S. M., Nassim, J. S., Hersey, E. M., & Kourosh, A. S. (2021). Prevention and correction of paradoxical masseteric bulging following botulinum toxin injection for masseter hypertrophy.

https://www.sciencedirect.com/science/article/pii/S2352647521000411?via%3Dihub

Dr. Aurora Kalmanson

Always Consult a Medical Specialist

The information provided in this blog is for informational and educational purposes only and should not be interpreted as personalized medical advice. It's crucial to understand that while we are medical professionals, the insights and advice we provide are based on general research and studies. They are not tailored to individual health needs or conditions. Thus, it is essential to consult directly with a healthcare provider who can offer personalized medical advice relevant to your specific situation.