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Headache After Cheek Filler – Causes and How to Treat Them

Medically Reviewed
Medically Reviewed by Dr. Aurora Kalmanson on
Written by Fillers Editorial Team, plastic surgery specialists.

Headaches after cheek filler injections are a common side effect that many patients experience. These headaches typically result from inflammation, muscle tension, and the body’s response to the injection process.

Most post-filler headaches are temporary, lasting from a few days to two weeks, and can be managed with simple at-home remedies. However, in rare cases, severe or persistent headaches may indicate complications that require medical attention. Understanding the causes, types, and duration of these headaches can help patients better prepare for their recovery and know when to seek professional help.

Understanding the Causes of Headaches After Cheek Fillers

Headaches following cheek filler injections can occur due to various factors related to the procedure and the body’s response to the treatment.

Inflammation From The Injection Process

Body’s Response to Foreign Substance: When dermal fillers are injected into the cheek area, the body recognizes them as foreign substances. This triggers an immune response, leading to localized inflammation at the injection sites. The body releases chemicals like histamines, which cause blood vessels to dilate and tissues to swell. This inflammatory process can put pressure on surrounding nerves and blood vessels, potentially resulting in headache pain.

Swelling and Irritation at Injection Sites: The physical act of injecting fillers can cause trauma to the delicate facial tissues. This trauma leads to swelling and irritation in the treated areas. As the cheeks are in close proximity to the temples and sinuses, swelling in this region can create pressure that radiates to surrounding areas, causing headache-like sensations. The extent of swelling can vary from person to person and depends on factors such as the type of filler used, the volume injected, and individual patient characteristics.

Hyaluronic Acid-Based Fillers Attracting Water: Many popular cheek fillers, such as Juvederm and Restylane, are composed of hyaluronic acid (HA). HA is a naturally occurring substance in the body known for its ability to attract and retain water. When injected, these HA-based fillers draw water to the injection sites, which can increase swelling in the days following the procedure. This additional fluid retention can contribute to pressure build-up in the facial tissues, potentially exacerbating headache symptoms.

Muscle Tension and Bruising

Filler Lifting and Stretching Facial Skin: When dermal fillers are injected into the cheek area, they create volume that lifts and stretches the facial skin. This sudden change in skin tension can lead to discomfort and headaches. The filler material pushes against the surrounding tissues, causing them to expand and adapt to the new shape. This stretching effect can put pressure on nerve endings in the skin and underlying structures, potentially triggering pain signals that manifest as headaches. Additionally, the lifting effect can alter the normal resting position of facial muscles, forcing them to work differently to maintain facial expressions, which may contribute to muscle fatigue and tension headaches.

Tension in Zygomaticus Major and Orbicularis Oculi Muscles: The injection of fillers in the cheek area can directly affect the zygomaticus major and orbicularis oculi muscles. The zygomaticus major is responsible for lifting the corners of the mouth when smiling, while the orbicularis oculi surrounds the eye and is involved in blinking and facial expressions. When fillers are introduced near these muscles, they can cause temporary stiffness or altered muscle function. This can result in increased tension as the muscles adjust to the presence of the filler. The tension in these muscles can radiate to surrounding areas, potentially causing headaches that feel like a tight band around the head or pain that extends from the cheeks to the temples and forehead.

Internal Bruising from Needle Injury: The injection process itself can cause internal bruising, even when performed by skilled practitioners. As the needle penetrates the skin and deeper tissues, it may damage small blood vessels, leading to bruising beneath the skin’s surface. This internal bruising can create pressure on nearby nerves and tissues, contributing to localized pain and headaches. The body’s healing response to this micro-trauma involves inflammation, which can further exacerbate the pressure and discomfort. While visible bruising may not always be apparent, internal bruising can still occur and may take several days to resolve, during which time patients may experience ongoing headache symptoms as the body works to repair the injured tissues.

Rare Side Effects Like Vascular Occlusion

Injected Gel Cutting Off Blood Supply to Facial Tissue: In rare cases, dermal filler injections can lead to vascular occlusion, a serious complication where the injected gel accidentally blocks blood flow in a blood vessel. This occurs when the filler material enters an artery or vein, either through direct injection or by compressing the vessel from the outside. The interruption of blood supply can affect various facial structures, including skin, muscles, and nerves. Patients may experience sudden, severe pain or headaches as the affected tissues become deprived of oxygen and nutrients. This condition requires immediate medical attention to prevent potential tissue damage or necrosis. Prompt recognition and treatment, often involving the use of hyaluronidase to dissolve hyaluronic acid-based fillers, are crucial to restore blood flow and prevent long-term complications.

Ischemia and Inflammation in Facial Structures: When vascular occlusion occurs, it can lead to ischemia, a condition where tissues are deprived of adequate blood supply and oxygen. This ischemia triggers an inflammatory response as the body attempts to address the lack of blood flow. The combination of ischemia and inflammation can cause severe, throbbing headaches that may be accompanied by other symptoms such as blanching or discoloration of the skin, intense pain in the affected area, and potential vision changes if occlusion affects blood vessels near the eyes. The inflammatory process can exacerbate the headache by causing swelling and putting pressure on surrounding nerves. If left untreated, prolonged ischemia can lead to tissue death and permanent damage, underscoring the importance of immediate medical intervention when symptoms of vascular occlusion are suspected following filler injections.

Stress and Anxiety Related to Injectable Procedures: The psychological aspects of undergoing cosmetic procedures, including cheek filler injections, can significantly contribute to the development of headaches. Many patients experience heightened stress and anxiety before, during, and after the treatment. This emotional strain can manifest physically, leading to muscle tension, particularly in the neck, shoulders, and facial areas. The anticipation of pain or potential complications, coupled with the pressure to achieve desired aesthetic results, can trigger a stress response in the body. This response may cause the release of stress hormones, such as cortisol and adrenaline, which can increase blood pressure and muscle tension, potentially resulting in stress-induced headaches. Additionally, the unfamiliarity of the procedure and the vulnerability felt during the injection process can worsen anxiety levels, further contributing to the onset of tension headaches or migraines in susceptible individuals.

At-Home Remedies for Treating Headaches After Cheek Filler Injections

For those experiencing headaches following cheek filler injections, several at-home remedies can provide relief. These methods aim to reduce inflammation, reduce pain, and promote healing without interfering with the filler’s effectiveness.

Cold Compresses to Reduce Inflammation

Applying cold compresses to the treated areas is a highly effective method for managing post-filler headaches. This technique works by constricting blood vessels, which helps reduce swelling and inflammation in the injected areas. The cold also has a numbing effect, providing immediate relief from pain and discomfort. To use this method, wrap an ice pack or a bag of frozen vegetables in a soft cloth to protect the skin from direct cold exposure. Apply the compress to the cheeks and temple areas for 15-20 minutes at a time, several times a day, especially during the first 48 hours after the procedure. This not only helps alleviate headache symptoms but can also minimize bruising and promote faster healing of the injection sites.

Over-The-Counter Pain Medication

Ibuprofen: This nonsteroidal anti-inflammatory drug (NSAID) is often recommended for managing headaches after cheek filler injections. Ibuprofen works by reducing inflammation and relieving pain, making it particularly effective for addressing the swelling and discomfort associated with filler procedures. It’s generally safe for most individuals and can be taken every 4-6 hours as needed. However, it’s important to follow the recommended dosage and not exceed the maximum daily limit. Some practitioners may advise against using ibuprofen immediately after the procedure as it can potentially increase the risk of bruising. Therefore, it’s crucial to consult with the healthcare provider who administered the fillers before taking ibuprofen, especially within the first 24-48 hours post-treatment.

Acetaminophen: This over-the-counter pain reliever is often recommended as a first-line treatment for headaches following cheek filler injections. Unlike ibuprofen, acetaminophen does not have anti-inflammatory properties but works effectively to reduce pain and fever. It’s generally considered safe for use immediately after filler treatments as it doesn’t affect blood clotting or increase the risk of bruising. Acetaminophen can be taken every 4-6 hours as needed, but it’s crucial to stick to the recommended dosage to avoid potential liver damage. For patients with pre-existing liver conditions or those taking other medications containing acetaminophen, it’s essential to consult with a healthcare provider before use. While effective for pain relief, acetaminophen may not address the underlying inflammation as effectively as NSAIDs.

Naproxen: This is another NSAID that can be effective in managing headaches and inflammation after cheek filler injections. Naproxen offers longer-lasting pain relief compared to ibuprofen, often requiring doses only every 8-12 hours. It works by reducing the production of prostaglandins, substances in the body that cause inflammation, pain, and fever. While effective, naproxen should be used with caution, especially in the immediate post-procedure period, as it can potentially increase the risk of bruising due to its blood-thinning properties. Patients should always consult with their healthcare provider before using naproxen, particularly if they have a history of stomach ulcers, bleeding disorders, or are taking other medications. As with all NSAIDs, it’s important to take naproxen with food to minimize the risk of stomach irritation.

Gentle Temple/Forehead Massage for Muscle Tension Relief

Incorporating gentle massage techniques can significantly alleviate headaches stemming from muscle tension after cheek filler injections. This method works by promoting blood circulation, relaxing tense muscles, and potentially stimulating the release of endorphins, the body’s natural pain relievers. To perform the massage, use fingertips to apply gentle, circular motions to the temples, forehead, and the base of the skull. It’s crucial to avoid direct pressure on the filler injection sites, especially in the first few days post-treatment. Start with light pressure and gradually increase as tolerated, being mindful of any discomfort. This technique can be particularly effective when combined with deep, slow breathing to enhance relaxation. Regular, short massage sessions throughout the day can help maintain muscle relaxation and provide ongoing headache relief.

Staying Hydrated and Avoiding Strenuous Exercise

Maintaining proper hydration is crucial for managing headaches after cheek filler injections. Adequate water intake helps flush out toxins, reduces inflammation, and supports the body’s healing processes. Aim for at least 8-10 glasses of water daily, which can help alleviate headache symptoms and promote overall recovery. Simultaneously, it’s important to avoid strenuous exercise for at least 24-48 hours post-treatment. Vigorous physical activity can increase blood flow to the face, potentially making swelling and discomfort worse. High-impact exercises or those that involve bending over should be particularly avoided as they can increase pressure in the head and face. Instead, gentle walks or light stretching can promote circulation without risking complications. This combination of hydration and exercise moderation supports the body’s natural healing process and helps minimize the duration and intensity of post-filler headaches.

Rest and Limiting Activity with Head Elevated

Adequate rest with the head in an elevated position is a simple yet effective strategy for managing headaches after cheek filler injections. Elevating the head, particularly while sleeping or resting, helps reduce blood flow to the face, which in turn minimizes swelling and pressure that can contribute to headache pain. Aim to keep the head propped up on pillows at a 30-45 degree angle for the first 24-48 hours post-treatment. This position also aids in proper lymphatic drainage, facilitating the removal of excess fluids from the treated areas. Limiting physical activity during this period is equally important, as it allows the body to focus its energy on healing and reduces the risk of displacing the filler or aggravating sensitive tissues. Engaging in calm, restful activities like reading or watching television can provide distraction from discomfort while sticking to the necessary recovery guidelines.

When to See a Doctor for Persistent, Severe Headaches

Sudden Vision Changes or Loss of Coordination: Any abrupt changes in vision or loss of coordination following cheek filler injections require immediate medical evaluation. These symptoms could indicate a serious complication such as vascular occlusion, where filler material has entered a blood vessel, potentially affecting blood supply to the eyes or brain. Vision changes might include blurriness, double vision, or even partial or complete loss of sight in one or both eyes. Loss of coordination, such as difficulty walking straight or maintaining balance, could suggest neurological involvement. These symptoms, especially when accompanied by severe pain, may signal an emergency situation that requires urgent intervention. Prompt medical attention is critical in these cases, as early treatment can prevent permanent damage to the eyes or other vital structures.

Severe Headache Pain Persisting for Over 72 Hours: Headaches that remain severe and unrelenting for more than 72 hours after cheek filler injections are a cause for concern and warrant medical evaluation. While some discomfort is expected in the days following the procedure, persistent intense pain could indicate complications such as infection, excessive swelling, or improper filler placement. This prolonged severe pain might be accompanied by other symptoms like fever, increased redness, or warmth at the injection sites. It’s important to distinguish between normal post-procedure discomfort and abnormal pain levels. If over-the-counter pain medications and recommended at-home remedies fail to provide relief after three days, it’s crucial to contact the healthcare provider who performed the procedure or seek immediate medical attention to rule out any serious complications.

Unusual Swelling Rapidly Worsening on One Side: Rapid and asymmetrical swelling following cheek filler injections, particularly if it’s worsening on one side of the face, is a red flag that requires prompt medical evaluation. While some swelling is normal after the procedure, a sudden increase in swelling that is disproportionate on one side could indicate several serious complications. This might include an allergic reaction to the filler, infection, or vascular occlusion. The swelling may be accompanied by pain, redness, or a feeling of tightness in the affected area. In some cases, this asymmetrical swelling can also affect neighboring areas like the eye or mouth on the same side. Immediate medical attention is crucial in these situations, as early intervention can prevent potential long-term complications and ensure proper treatment, which may include dissolving the filler or administering specific medications to address the underlying cause.

Migraines Getting More Frequent or Intense: If migraines become more frequent or intense following cheek filler injections, it’s crucial to seek medical attention promptly. This escalation in migraine activity could indicate an underlying complication or an unexpected interaction between the filler and surrounding tissues. Increased frequency or severity of migraines might suggest pressure on nerves, blood vessels, or other sensitive structures in the face. It could also be a sign of an inflammatory response that’s more severe than anticipated. In some cases, this change in migraine patterns could be related to the placement of the filler or an unexpected spreading of the product. A healthcare professional can assess whether the migraines are directly related to the filler injection or if there’s another underlying cause. They may recommend imaging studies or consider dissolving the filler if it’s determined to be the source of the problem.

Muscle Weakness Making It Hard to Chew or Move Facial Muscles: Experiencing muscle weakness that affects chewing or general facial movements after cheek filler injections is a serious concern that requires immediate medical evaluation. This symptom could indicate several potential complications, including unintended spread of the filler to surrounding muscle groups or pressure on facial nerves. In rare cases, it might suggest a more severe complication such as facial nerve paralysis or a reaction affecting the neuromuscular junction. Difficulty in performing basic facial movements or chewing food not only impacts daily functions but could also signal a risk to vital processes like speaking and swallowing. A healthcare provider needs to assess the extent and nature of the weakness promptly. They may conduct a physical examination, neurological tests, or imaging studies to determine the cause and appropriate treatment, which could range from observation and supportive care to immediate intervention to dissolve or remove the filler.

Frequently Asked Questions

How common are headaches after cheek filler injections?

Headaches are a fairly common side effect after cheek filler injections, usually due to inflammation or muscle tension in the treated area.

Can headaches be a sign of a serious complication after filler injections?

While most headaches are mild and temporary, persistent or severe headaches could indicate a more serious complication like vascular occlusion, and you should contact your doctor if you experience these symptoms.

How long do headaches typically last after cheek filler injections?

Headaches usually last from a few days up to two weeks after cheek filler injections, with the most intense pain occurring in the first 48 hours.

Is it normal to experience migraines after getting cheek fillers?

Yes, some patients do experience migraines after cheek fillers due to the body's response to the injection, but they should subside within a few days to a week.

Should I contact my doctor if I experience severe headaches after cheek fillers?

Yes, you should contact your doctor if you experience severe headaches that do not improve with over-the-counter medications or if they persist beyond 72 hours.

Conclusion

Headaches after cheek filler injections are common but typically temporary, usually resolving within one to two weeks. Understanding the causes, types, and duration of these headaches can help in managing post-treatment symptoms effectively. At-home remedies such as cold compresses, over-the-counter pain medication, and proper rest can provide relief. However, persistent, severe, or unusual symptoms warrant immediate medical attention to rule out complications. Staying informed and vigilant can ensure a smoother recovery and help you achieve the desired aesthetic results safely.

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References:

Colon, J., Mirkin, S., Hardigan, P., Elias, M. J., & Jacobs, R. J. (2023). Adverse Events Reported From Hyaluronic Acid Dermal Filler Injections to the Facial Region: A Systematic Review and Meta-Analysis.

https://www.cureus.com/articles/148694-adverse-events-reported-from-hyaluronic-acid-dermal-filler-injections-to-the-facial-region-a-systematic-review-and-meta-analysis#!/

Dr. Aurora Kalmanson

Always Consult a Medical Specialist

The information provided in this blog is for informational and educational purposes only and should not be interpreted as personalized medical advice. It's crucial to understand that while we are medical professionals, the insights and advice we provide are based on general research and studies. They are not tailored to individual health needs or conditions. Thus, it is essential to consult directly with a healthcare provider who can offer personalized medical advice relevant to your specific situation.