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Versa Lip Filler vs Juvederm – Which Is Best for You?

Medically Reviewed
Medically Reviewed by Dr. Aurora Kalmanson on
Written by Fillers Editorial Team, plastic surgery specialists.

Versa and Juvederm are two leading hyaluronic acid-based dermal fillers used for lip augmentation and facial rejuvenation. Both offer effective solutions for adding volume, smoothing wrinkles, and enhancing lip shape, but they have some key differences in formulation and characteristics.

Versa utilizes a proprietary Thixofix cross-linking technology that creates a smooth, uniform gel for natural-looking results lasting up to 12 months. Juvederm employs Vycross technology, resulting in a slightly thicker consistency that can provide more dramatic volume for 6-18 months depending on the specific product. While Versa may offer less swelling and a softer feel, Juvederm has a longer track record and more product options for customized treatments. The choice between these fillers ultimately depends on the patient’s unique anatomy, aesthetic goals, and injector preference.

Key Differences Between Versa and Juvederm Lip Fillers

Versa and Juvederm lip fillers share many similarities as hyaluronic acid-based injectables, but have some notable differences in their formulations, injection techniques, and expected outcomes. Understanding these distinctions can help patients and providers select the most appropriate option.

Composition and Crosslinking Technology

Versa’s Thixofix Technology: Versa utilizes a proprietary cross-linking process called Thixofix to create its hyaluronic acid gel filler. This technology results in perfectly spherical, uniform particles that are designed to integrate smoothly with the surrounding tissues. The Thixofix method allows for a high degree of malleability, making Versa easier to mold and shape during injection. This can lead to a more natural look and feel in the lips. The uniform particle size also contributes to Versa’s reputation for minimal swelling post-treatment, as the body’s inflammatory response is less pronounced compared to fillers with irregular particle shapes.

Juvederm’s Vycross Technology: Juvederm employs Vycross technology in its more recent formulations, which combines different molecular weights of hyaluronic acid. This results in a tighter, more cohesive gel network that can provide longer-lasting results and potentially more lift and structure. The Vycross technology allows for a smoother consistency that flows easily through the needle during injection, while still maintaining its shape once placed in the tissue. This can be particularly beneficial for creating defined lip borders or addressing deeper lines around the mouth. The varied molecular weights of hyaluronic acid in Juvederm also contribute to its ability to attract and retain moisture, potentially enhancing the plumping effect over time.

Consistency and Injection Experience

Versa’s Smooth and Uniform Gel: The consistency of Versa lip filler is characterized by its smooth and uniform texture. This property is a direct result of the Thixofix technology used in its production, which creates gel particles of consistent size and shape. The uniformity of Versa’s gel allows for a more predictable and even distribution when injected into the lips or surrounding areas. This can be particularly advantageous when aiming for subtle enhancements or when working with patients who have thin or delicate lip tissue. The smooth consistency also contributes to a more comfortable injection experience for patients, as the product flows easily through the needle with minimal resistance. Additionally, the uniform nature of Versa’s gel is associated with reduced post-treatment swelling, which can be appealing to patients seeking a more immediate return to their daily activities after the procedure.

Juvederm’s Thicker and More Granular Gel: Juvederm’s gel consistency is characterized by a thicker and slightly more granular texture compared to Versa. This unique composition is a result of Juvederm’s proprietary Vycross technology, which combines different molecular weights of hyaluronic acid. The thicker consistency allows for greater structural support and volume enhancement, making it particularly effective for addressing deeper wrinkles and folds or creating more dramatic lip augmentation. The granular nature of the gel contributes to its ability to integrate with surrounding tissues, providing a natural-looking result. However, this texture may also lead to slightly more noticeable initial swelling post-treatment compared to smoother gels like Versa.

Longevity of Results

Versa – Up to 12 Months: Versa lip filler is known for its ability to provide long-lasting results, with effects typically enduring for up to 12 months. This duration is attributed to the unique Thixofix cross-linking technology used in Versa’s formulation, which creates a stable gel structure that resists breakdown in the body. The longevity of Versa is also influenced by its uniform particle size, which allows for even distribution and integration within the tissue. Factors such as individual metabolism, lifestyle habits, and the specific area treated can impact the duration of results. Some patients may find that the effects of Versa gradually diminish over time, with optimal results maintained for the first 6-9 months before a gradual return to the pre-treatment state.

Juvederm – 6-18 Months (Depending on Product): The longevity of Juvederm fillers varies significantly depending on the specific product used and the area treated. Juvederm’s range of products is designed to address different concerns and provide varying durations of effect. For instance, Juvederm Ultra and Ultra Plus typically last 6-12 months when used for lip augmentation, while Juvederm Volbella can provide results for up to 12 months or more. Juvederm Voluma, used for cheek augmentation, can last up to 18-24 months. The extended longevity of some Juvederm products is attributed to the Vycross technology, which creates a more stable gel structure. Factors such as the patient’s age, skin type, and lifestyle can also influence how long the results last.

Presence of Lidocaine

Versa Contains Lidocaine for Added Comfort: Versa lip filler is formulated with lidocaine, a local anesthetic, to enhance patient comfort during the injection process. The inclusion of lidocaine in the filler solution provides an immediate numbing effect as the product is injected, significantly reducing pain and discomfort associated with the procedure. This feature is particularly beneficial for patients with sensitive lips or those who experience anxiety about injections. The lidocaine in Versa begins working within seconds of injection, allowing for a more pleasant treatment experience. It’s important to note that while lidocaine improves comfort, it does not compromise the filler’s effectiveness or longevity. Patients with known allergies to lidocaine should inform their provider before treatment.

Some Juvederm Products Lack Lidocaine: While many Juvederm products contain lidocaine for patient comfort, some formulations in the Juvederm range do not include this local anesthetic. The original Juvederm formulations were introduced without lidocaine, and these versions are still available for patients who prefer or require a lidocaine-free option. For products without lidocaine, practitioners often apply a topical numbing cream before the procedure or use other pain management techniques. The absence of lidocaine in some Juvederm products can be advantageous for patients with lidocaine sensitivities or those who prefer to avoid anesthetics. However, it’s worth noting that most modern Juvederm products, such as Juvederm Ultra XC and Volbella XC, do contain lidocaine, offering the same comfort benefits as Versa.

Injection Techniques and Considerations

Importance of Injector Expertise and Technique

The skill and experience of the injector play a crucial role in achieving optimal results with both Versa and Juvederm lip fillers. A thorough understanding of facial anatomy, including the location of blood vessels and nerves, is essential for safe and effective treatment. Experienced practitioners employ various injection techniques, such as serial puncture, linear threading, or fanning, depending on the specific area and desired outcome. They also consider factors like lip shape, facial proportions, and individual patient goals when determining the injection strategy. Proper technique not only ensures aesthetic results but also minimizes the risk of complications such as lumps, asymmetry, or vascular occlusion. Patients should always seek treatment from certified professionals with a proven track record in lip augmentation to ensure the best possible outcomes.

Injection Depth and Placement

Versa – Mid-Dermis: Versa lip filler is typically injected into the mid-dermis layer of the skin. This placement allows for optimal integration with the surrounding tissue, providing natural-looking results with minimal risk of lumpiness or surface irregularities. The mid-dermal injection technique is particularly effective for addressing fine lines and wrinkles around the lips, as well as enhancing lip definition. The smooth consistency of Versa makes it well-suited for this depth, allowing for even distribution and a soft, natural feel. Injectors often use a combination of techniques, such as linear threading or serial puncture, to ensure proper placement and achieve the desired outcome. The mid-dermal placement also contributes to the longevity of Versa results, as the filler is less likely to migrate or be rapidly metabolized in this layer.

Juvederm – Mid-Dermis to Subcutaneous Tissue: Juvederm fillers offer versatility in injection depth, ranging from mid-dermis to subcutaneous tissue, depending on the specific product and desired outcome. For lip enhancement, Juvederm products like Volbella are often placed in the mid-dermis, similar to Versa, to address fine lines and provide subtle volume. However, for more significant volumization or structural support, Juvederm Ultra or Voluma may be injected into the subcutaneous layer. This deeper placement allows for more dramatic results and can provide lift to the lip area. The ability to inject at various depths makes Juvederm suitable for a wide range of lip enhancement goals, from subtle refinement to more pronounced augmentation. The choice of injection depth is carefully considered by experienced practitioners to ensure natural-looking results that complement the patient’s facial anatomy.

Customizing Treatment Based on Patient Goals and Anatomy: The art of lip enhancement lies in adapting the treatment to each patient’s unique facial features and aesthetic aspirations. Skilled practitioners assess factors such as lip shape, facial proportions, and skin quality to determine the most appropriate filler and injection technique. They consider the patient’s desired outcome, whether it’s subtle volume enhancement, lip definition improvement, or correction of asymmetry. The treatment plan may involve combining different injection depths and techniques to achieve a harmonious result. For instance, deeper injections might be used to provide structure, while superficial injections address fine lines. This customized approach ensures that the lip enhancement complements the patient’s overall facial aesthetics, resulting in natural-looking, balanced outcomes that align with individual goals.

Frequently Asked Questions

How long do Versa and Juvederm lip fillers typically last?

Versa lip fillers usually last up to 12 months, while Juvederm lip fillers can last anywhere from 6 to 18 months, depending on the specific product used and the treated area.

Is one filler better than the other for achieving natural-looking results?

Both Versa and Juvederm are effective in achieving natural-looking results. The choice between them depends on individual goals and the injector's expertise, as both fillers can be tailored for subtle or more pronounced enhancements.

Can Versa and Juvederm be used together for lip enhancement?

Yes, Versa and Juvederm can be used together for lip enhancement. Some providers may combine these fillers to take advantage of their unique properties and achieve a more customized outcome.

How often can I get lip filler treatments with Versa or Juvederm?

You can generally get lip filler treatments with Versa or Juvederm once the initial effects start to diminish, which is typically after 6-12 months. However, it’s important to consult with your provider to determine the appropriate timing based on your individual needs.

Will my lips feel different after getting Versa or Juvederm fillers?

After receiving Versa or Juvederm fillers, your lips may temporarily feel slightly firmer or tender, but these sensations usually subside within a few days. Your lips should feel natural once they have fully settled.

Conclusion

In summary, both Versa and Juvederm are excellent options for lip enhancement, offering long-lasting and natural-looking results. Choosing between these fillers depends on individual preferences, goals, and the expertise of the provider. While Versa may provide smoother consistency and minimal swelling, Juvederm offers a range of products for various cosmetic needs. Regardless of the choice, ensuring a thorough consultation and selecting a qualified injector are critical steps for achieving the best outcomes. With proper care and follow-up, patients can enjoy fuller, more youthful lips for an extended period.

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References:

Park, K. E., Mehta, P., Kherani, F., Lee, W. W., Woodward, J. A., Foster, J. A., & Zhang-Nunes, S. (2023). Response of 21 Hyaluronic Acid Fillers to Recombinant Human Hyaluronidase.

https://journals.lww.com/prsgo/fulltext/2023/12000/response_of_21_hyaluronic_acid_fillers_to.55.aspx

Akinbiyi, T., Othman, S., Familusi, O., Calvert, C., Card, E. B., & Percec, I. (2020). Better Results in Facial Rejuvenation with Fillers.

https://journals.lww.com/prsgo/fulltext/2020/10000/better_results_in_facial_rejuvenation_with_fillers.17.aspx

Dr. Aurora Kalmanson

Always Consult a Medical Specialist

The information provided in this blog is for informational and educational purposes only and should not be interpreted as personalized medical advice. It's crucial to understand that while we are medical professionals, the insights and advice we provide are based on general research and studies. They are not tailored to individual health needs or conditions. Thus, it is essential to consult directly with a healthcare provider who can offer personalized medical advice relevant to your specific situation.